Osmosis Jones: Chris Rock	Thrax: Laurence Fishburne
Leah: Brandy Norwood	Drix: David Hyde Pierce
Mayor Phlemming: William Shatner	Mrs. Boyd: Molly Shannon
Bob: Chris Elliott	Frank: Bill Murray
Shane: Elena Franklin	Director: Bobby & Peter Farrelly

30 Second Bottom Line: A man who literally eats with the manners of a pig is threatened with death when he becomes sick after ingesting a dirty boiled egg and later an oyster loaded with germs.

Story Line: Frank (Bill Murray) is a widowed father who works at a zoo and has a pre teen daughter named Shane (Elena Franklin). He is a slob, who both looks and acts the part. Shane wants him to take her hiking but he'd rather go to a chicken wing eating festival for some serious bingeing. While at the zoo one day, Frank eats a boiled egg that has been in the mouth of a monkey, and was then dropped to the ground. He's such a slob that it doesn't occur to him that he might get sick because of this.

The creativity of this picture becomes clear soon after he eats the egg. We travel inside Frank's body to a city where various locations (stomach, throat, etc.) are neighborhoods that house a community with an animated mayor, police force, newscaster at an anchor desk and most importantly, good and evil. Thrax (Laurence Fishburne) is a bad man who wants to get Frank's temperature up to 108 degrees because that will kill him. However, Thrax is not satisfied with the death unless it's done in less than 48 hours so he can boast the record for the fastest kill.

To the rescue comes Osmosis Jones (Chris Rock), a policeman, and his sidekick Drix (David Hyde Pierce). Jones is a white blood cell cop, who along with Drix, an oversized capsule sort of like a huge Tylenol, join forces to save Frank from the poisonous Thrax.

Mayor Phlemming (William Shatner) is running for reelection in Frank City, and his assistant Leah (Brandy Norwood) is forced to choose sides between her allegiance to the Mayor and her fondness for Osmosis. Two other live action characters rounding out the story are Uncle Bob (Chris Elliott), Frank's fellow slob and Shane's science teacher, Mrs. Boyd (Molly Shannon). She manages to be on the receiving end of bodily fluids from Frank, which gives the film its best gross out factors.

Tell Me More About It: In looking at the trailer and reading about the film prior to seeing it, I was not quite sure what to expect. A film that tells the story of the human body one moment, as we are used to seeing it, from the outside, and then switches to the inside, where the body is an animated world, is difficult to conceptualize. Looking at the clever sequences where germs and medicine are themselves people is a mind-expanding concept. As one would expect, if the Farrelly brothers make a movie, bodily fluids and the release of gasses through various cavities will be a feature of the film. I find these events funny here because of the creativity with which they were done.

The Osmosis Jones script is so tight, that it makes me wonder how many folks it took to write all of the clever lines and develop the complex interplay between the city of animated characters within the body.

Although the story starts out routinely, the genius of the writing and acting quickly come together. Just when I thought I was too tired to listen to the voice of Chris Rock any longer, he got on my last nerve in Jay and Silent Bob Strike Back), he surprised me with the portrayal of an animated character, as real as Bob and Shane. While this may not be worthy of a sequel, it's a good comedy to take kids to who want gross jokes without being stupid. For both adults and kids, Osmosis Jones delivers.

Chris Rock: Jay and Silent Bob Strike Back	Laurence Fishburne: Once in the Life
Brandy Norwood: Moehsa-TV	David Hyde Pierce: Wet Hot American Summer
William Shatner: Miss Congeniality	Molly Shannon: Dr. Doolittle 2
Chris Elliott: Scary Movie 2	Bill Murray: The Royal Tenenbaums
Elena Franklin: Debut	The Farrelly's: Shallow Hal